The clerkship curriculum that evolved into the ideas for this edition was inspired by two talented and forthright students, Philbert Yao and Chuck Rosipal, who have since graduated from medical school. It has been a tremendous joy to work with the excellent pediatricians at the McGovern Medical School at the University of Texas Health Science Center (UTHealth) at Houston. I am greatly indebted to my editor, Bob Boehringer, whose experience and vision helped to shape this series. I appreciate McGraw Hill’s believing in the concept of teaching through clinical cases, and I would like to especially acknowledge Catherine Saggese for her production expertise, Madison Tucky for her editorial guidance, and Revathi Viswanathan for her excellent production skills. At the McGovern Medical School at Houston, I appreciate Dr. Barbara Stoll, our recently retired Dean, for her support. Without the encouragement from my chairman Dr. Sean Blackwell, a wonderful clinician, administrator, scientist, and leader, and Dr. Patricia Butler, Vice Dean for Educational Programs, who inspires us all to be excellent educators, I could not have succeeded in this endeavor. Two medical students—Joy Davis and Heba Ahmad—were instrumental in providing excellent feedback and recommendations. I continue to marvel at my daughter Allison’s amazing intellectual, clinical, and writing ability, effortlessly elevating the quality of our Case Files manuscripts. Most of all, I appreciate my ever-loving wife Terri, and my four wonderful children Andy and his wife Anna, Michael and his wife Nadine, Allison, and Christina and her husband Andy, for their patience and understanding in the writing process.